“Noninvasive prenatal genetic testing (NIPT) is recommended to every pregnant women”
(Americal Congress of Obstetricians and Gynecologists, ACOG)
NIPT are performed non-invasively, without any risk to a mother and a child.
NIPT are several times more accurate that other prenatal screening tests
NIPT are the most rapidly adopted tests in clinical practice
Noninvasive prenatal test (NIPT) is a modern and the most accurate genetic test for screening of chromosomal abnormalities in an unborn child by analysing blood of pregnant women.
NIPT assesses the risk of common chromosomal disorders (aneuploidies), such as Down (trisomy of chromosome 21 [T21]), Edvards (trisomy of chromosome 18 [T18]) and Patau (trisomy of chromosome 13 [T13]) syndromes in an unborn child already from 10 week of pregnancy.
Additionally, fetal sex, the risk of sex chromosomes abnormalities and some microdeletions syndromes can be evaluated. In our clinic we perform the extensively clinically validated and the most accurate HARMONY NIPT.
(Hassold T. & Hunt P. “To err (meiotically) is human: the genesis of human aneuploidy”. Nature Reviews Genetics, 2001 Apr;2(4):280-91)
NIPT results allow parents to make informed choices about the pregnancy and children future
The risk of trisomies is increasing with maternal age
The most common chromosomal disorders associated with mental retardation, malformation of various organs are abnormalities of chromosome number (aneuploidies), especially additional (third) their copy (trisomy). The frequency of trisomies particularly rapidly increases with maternal age. The trisomies of chromosomes 21 (Down s.), 18 (Edwards s.) and 13 (Patau s.) are the most frequent genetic disorders, that adversely affects the physical and mental development of a baby.
Nonnvasive prenatal tests (NIPT) is the most accurate screeening method of these serious disorders, which is recommended by experts for ALL pregnant women.
0%
More than half of Down syndrome cases are born to women under 35 years
100 in 200
1 in 200 newborn is affected by chromosomal disorder
100 in 600
1 in 600 newborn is affected by Down syndrome
The risk (%) of trisomies and Down syndrome (T21) according to maternal age
The risk for chromosome problems increases with the mother’s age. Most babies with Down syndrome are born to women under the age of 35. This is because women under the age of 35 have more babies than women over 35 (higher fertility). Therefore NIPT is recommended for all pregnant women regardless the age.
- Visos trisomijos
- Dauno sindromas (T21)
(Morris JK, Mutton DE, Alberman E. “Revised estimates of the maternal age specific live birth prevalence of Down’s syndrome.” J Med Screen. 2002;9(1):2-6.)
>0%
Very high NIPT accuracy (T21)
<10%
Very rare HARMONY NIPT false positive (FP) results (T21)
from40week
HARMONY NIPT is performed from 10 gestational week
Experienced clinical geneticist will thoroughly evaluate your unique case and timely prescribe NIPT test
Ramūnas Janavičius
Med. m. dr., gyd. genetikas